Anti Inflammatory Drugs

Diclofenac Sodium

Approx Price: Rs 40 / Box(s) 
Minimum Order Quantity: 100000 Box(s)
Each Uncoated Tablet Contains :-

Diclofenac
Diclofenac Sodium50 mg.
Paracetamol500 mg.

TYPICAL USAGE: Adnexitis, dysmenorrhoea, inflammation, migraine, post-operative pain, post-traumatic pain, rheumatoid arthritis.

MECHANISM OF ACTION: Diclofenac inhibits both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation.

Paracetamol

TYPICAL USAGE: Ear pain, fever, headache, malaise, migraine, mild to moderate pain, pain, post-vaccine reaction, short-bowel syndrome.

MECHANISM OF ACTION: Paracetamol is thought to act primarily in the CNS, increasing the pain threshold by inhibiting both isoforms of cyclooxygenase, COX-1, COX-2, and COX-3 enzymes involved in prostaglandin (PG) synthesis. Paracetamol indirectly blocks COX, and that this blockade is ineffective in the presence of peroxides. paracetamol is effective in the central nervous system and in endothelial cells but not in platelets and immune cells which have high levels of peroxides. The antipyretic properties of paracetamol are likely due to direct effects on the heat-regulating centres of the hypothalamus resulting in peripheral vasodilation, sweating and hence heat dissipation.

Additional Information:
  • Pay Mode Terms: T/T (Bank Transfer),Other
  • Delivery Time: 30 days
  • Packaging Details: Blister Pack
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